PhD Theses

  1. JPH Burbach (7-10-1980, co-promotor ER de Kloet, promotor D de Wied) Proteolytic conversion of  endorphin and oxytocin in rat brain (Utrecht).
  2. HD Veldhuis (16-02-1982, co-promotor ER de Kloet, promotor D. de Wied) Receptors for adrenal steroids in rat hippocampus (Utrecht).
  3. JL Lebouille (1986, co-promotor ER de Kloet) -endorphin generating endopeptidase distribution, properties and hormonal regulation (Utrecht).
  4. JMHM Reul (16-06-1987, co-promotor ER de Kloet, promotor D de Wied) Two distinct corticosteroid receptor systems in rat brain: plasticity and putative function (Utrecht)
  5. P Rosenfeld (1988, co-promotor ER de Kloet, promotor S Levine) Ontogeny of corticosteroid receptors in the rat brain (Stanford)
  6. JPM Elands (8-06-1989, co-promotor ER de Kloet, promotor D de Wied) Neurohypophyseal hormone receptors (Utrecht).
  7. ThD Voorhuis (29-03-1990, co-promotor ER de Kloet, promotor D de Wied) Neurobiology of vasotocin in the canary (Utrecht).

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  1. JAM van Eekelen (1990) Neuroendocrine implications of brain corticosteroid receptor diversity (promotor ER de Kloet, Utrecht).
  2. H Sybesma (8-05-1991) Eltoprazine: 5HT-1 receptors and aggression (promotor ER de Kloet, Leiden).
  3. DW Koppenaal (5-06-1991) GnSIF:-physiology and mechanism of action (promotor ER de Kloet, co-promotor J de Koning).
  4. AMM van Erp (8-06-1993)  PVH & Grooming (promotor ER de Kloet, co-promotor M Kruk).
  5. DTWM van den Berg (2-12-1993) Stress: cardiovascular regulation and brain corticosteroid receptors (promotores ER de Kloet and W de Jong).
  6. J Wiegers (7-06-1995) Glucocorticoid hormone action in the immune system revisited (promotores ER de Kloet and F Holsboer).
  7. NY Rots (8-06-1995) Dopamine and stress: studies with genetically selected lines (promotores ER de Kloet and A Cools, Leiden).
  8. AD van Haarts (26-10-1995) Brain corticosteroid receptor function and neuroenodocrine regulation: genetically determines and pharmacogenetically provoked variations in corticosteroid action (promotor ER de Kloet).
  9. S Tio (22-11-1995) GnSIF/AF: purification and physiological aspects (promotor ER de Kloet, co-promotor J de Koning ).
  10. OC Meijer (28-11-1996) Corticosterone and hippocampal 5HT-1A receptors: functional implications of central corticosteroid receptor diversity (promotor ER de Kloet).
  11. HJJ van Oers (17-06-1998) Maternal deprivation: implications for the ontogeny of the neural stress circuitry (promotores ER de Kloet and S Levine).
  12. JO Workel (17-06-1999) Maternal deprivation: implications for stress, cognition and aging (promotor ER de Kloet, co-promotor M. Oitzl).
  13. MJM Schaaf (22-06-1999) Corticosterone, BDNF and memory formation: (promotor ER de Kloet, co-promotor E Vreugdenhil)
  14. EGWM Lentjes (11-11-1999) Cortisol: bioavailability and receptors in stress-related disorders (promotores M Krans and ER de Kloet)
  15. JTJ Visser (20-01-2000) Cytokine regulation by glucocorticoids in the chronic fatigue syndrome (promotor ER de Kloet, co-promotor L Nagelkerken).
  16. EN Griep (5-10-2000) Fibromyalgia syndrome: neuroendocrine perspectives with clinical implications (promotor ER de Kloet).
  17. J Grootendorst (13-06-2001) Stress effects on cognitive performance of apolipoprotein E knockout mice: implications for Alzheimer's Disease (promotoror ER de Kloet, co-promotor MS Oitzl).
  18. M van Kampen (25-04-2002) Chronic psychosocial stress in male tree shrews: an animal model for depression (promotores ER de Kloet and E Fuchs).
  19. Th Rinne (28-5-2002) The neuroendocrine scars of sustained childhood abuse in adult female borderline personality disorder (promotores ER de Kloet and W van den Brink, Amsterdam).
  20. J. Schaap (31-10-2002) Neurons of the mammalian circadian pacemaker: cellular and network properties (promotor ER de Kloet, co-promotor dr J.H. Meijer).
  21. A. Veenema (23-6-2003) Coping style and stressor susceptibility: neuroendocrine and neurochemical studies with genetically selected mouse lines (promotores J Koolhaas and ER de Kloet, Groningen)
  22. D.E.M. Feldker (4-9-2003) Towards the molecular basis of individual differences in vulnerability to stress: application of large scale gene expression profiling (promotor ER de Kloet, co-promotor E Vreugdenhil)
  23. A. Karssen (30-10-2003) Glucocorticoid access to the Brain: involvement of the efflux transporter P-glycoprotein. (promotor ER de Kloet, co-promotor OC Meijer).
  24. M. Schmidt (15-1-2004) Programming the stress system in the neonatal brain: molecular mechanisms (promotor ER de Kloet)
  25. B.M. Engels (3-3-2005) Expression and functional characterization of doublecortin-like kinase splice variants  (promotor ER de Kloet, co-promotor E Vreugdenhil)
  26. M Morsink (June 26 2007) Glucocorticoid control of gene transcription in nervous tissue (promotor ER de Kloet, co-promotor NA Datson)
  27. L. Enthoven (october 4, 2007) Early life experience: outcome of single and repeated maternal absence (promotores ER de Kloet and MS Oitzl)
  28. I.E.M de Jong (October 17, 2007). Vulnerability to cocaine: role of stress hormones (promotor ER de Kloet, co-promotor MS Oitzl)
  29. Y Revsin (September 17, 2008)  Type 1 diabetes, glucocorticoids and the brain: a sweet connection (promoter ER de Kloet, co-promotor MS Oitzl)
  30. R. van der Veen (October 1, 2008)  Gene-environment interaction in early life and adulthood: implications for cocaine intake (promotores ER de Kloet and PV Piazza)
  31. S van der Laan (November 6, 2008) Expression and function of nuclear receptor coregulators in brain: understanding the cell specific effects of glucocorticoids (promotor ER de Kloet, co-promotor OC Meijer)
  32. V Brinks (februari 19, 2009) Stress, emotion and cognition: role of mineralo- and glucocorticoid receptors (promoters ER de Kloet and MS Oitzl)
  33. T Dijkmans (October 14, 2009) Doublecortin-like kinase and neuronal differentiation  (promotor ER de Kloet, co-promoter E Vreugdenhil)
  34. LWA van Hooijdonk (April 20, 2010) Glucocorticoid receptor knockdown and adult hippocampal neurogenesis. (promotor ER de Kloet, co-promoter E Vreugdenhil)
  35. A Berry (April  21, 2010) Oxidative stress, neuroendocrine function and behavior in an animal model of extended longevity. (promotor ER de Kloet, co-promotor F Cirulli)
  36. RA Sarabdjitsingh (July 1, 2010). Glucocorticoid pulsatility: implications for brain functioning  (promotor ER de Kloet, co-promotor OC Meijer)
  37. GJ Schenk (October 21, 2010).  Understanding doublecortin-like kinase gene function through transgenesis  (promotor ER de Kloet, co-promotor E Vreugdenhil)
  38. N van Leeuwen (November 9, 2010) Mineralocorticoid receptor gene variants: implications for stress, blood pressure and personality. (promotores FG Zitman and E.R. de Kloet, co-promotor RH de Rijk)
  39. N Daskalakis (december 8, 2011) Nurturing Nature: testing the three-hit hypothesis of schizophrenia. (promotor ER de Kloet, co-promotor MS Oitzl).
  40. MD Klok (December 15, 2011)  Mineralocorticoid receptor in human brain: a key player in riselience. (promotores ER de Kloet and FG Zitman, co-promotor RH de Rijk).
  41. SEM Claessens (June 27, 2012) Programming the Brain: towards intervention strategies (promotores ER de Kloet and MS Oitzl).
  42. S Dalm (November 21, 2012) Towards a mouse model of depression: a psychoneuroendocrine approach (promotores MS Oitzl and ER de Kloet).
  43. CS Verissimo (December 6, 2012) Doublecortin-like kinase: a potential therapeutic target for neuroblastoma (promotor ER de Kloet, co-promotores E Vreugdenhil and CP Fitzsimons).
  44. Y Aubert (December 11, 2012) Sex, aggression and pair-bond: a study on the serotonergic regulation of female sexual function in the marmoset monkey (promotores ER de Kloet and D Abbott, co-promotor NA Datson).
  45. N. Speksnijder (November 28, 2013) Determinants of Psychosis-Vulnerability: Focus on MEF2- and Glucocorticoid-Signaling (promotor ER de Kloet, co-promotor NA Datson).
  46. DJ Saaltink (juni 5, 2014) Doublecortin-like Knockdown in the Adult Mouse Brain: implications for neurogenesis, neuroplasticity and behaviour (Promotor ER de Kloet, Co-promotor E Vreugdenhil)
  47. I. Zalachoras (september 17, 2014) Selective Glucocorticoid Receptor Modulation: targeting the brain under stress (Promotor ER de Kloet, Co-promotor OC Meijer).
  48. FL Groeneweg (november 6, 2014) Corticosteroid receptor dynamics: analysis by advanced fluorescence microscopy (Promotor ER de Kloet, Co-promotor MJM Schaaf).
  49. JAP Polman (may 10, 2016) Glucocorticoid signature in a neuronal genomic context (Promotor ER de Kloet, Copromotor NA Datson).